ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Anthracene
Study details
Groupmammalian
OrganismMouse
TissueHepa lclc7 cells
Age
InVivoIn vitro
LabLaboratory
Flow
Duration24 hours
Route
Temperature
ConcentrationEC50: 42 to 150 nM
NotesContributes to TCDD-like activity of air particulate matter
Described effects
Effect on anti-estrogen: Induction of AhR-mediated gene expression
Effect on anti-estrogen: Relative potency to TCDD: 0.0001
Literature references
Clemons, J.H., Allan, L.M., Marvin, C.H., Wu, Z., McCarry, B.E., Bryant, D.W., Zacharewski, T.(1998). Evidence of estrogen- and TCDD-like activities in crude and fractionated extracts of PM10 air particulate material using in vitro gene expression assay.Environ. Sci. Technol., 32: 1853-1860
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.