ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Anthracene
Study details
Groupmammalian
OrganismChinese hamster
TissueCHO cells cotransfected with a hAR
Age
InVivoIn vitro
LabLaboratory
Flow
Duration24 hours
Route
Temperature37°C
Concentration10 µM
NotesAR assay; dose range: 0.05-10 µM
Described effects
Effect on anti-androgen: Slight inhibition of hAR transactivation by R1881
Literature references
Vinggaard, A.M., Hnida, C., Larsen, J.C.(2000). Environmental polycyclic aromatic hydrocarbons affect androgen receptor activation in vitro.Toxicology, 145: 173-183
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.