ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Methoxychlor
Study details
Groupmammalian
OrganismHuman
TissueERbeta
Age
InVivoIn vitro
LabLaboratory
Flow
Duration
Route
Temperature
Concentration
NotesQSAR based on CoMFA; observed log RBA 17-beta-estradiol: 2
Described effects
Effect on estrogen: Predicted log RBA: -1.08
Literature references
Xing, L., Welsh, W.J., Tong, W., Perkins, R., Sheehan, D.M.(1999). Comparison of estrogen receptor alpha and beta subtypes based on comparative molecular field analysis (CoMFA).SAR and QSAR in Environmental Research, 10: 215-237
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.