ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Methoxychlor
Study details
Groupmammalian
OrganismAlpk:APfSD rat, male
TissueAccessory sex organs
Age35-36 days
InVivoIn vivo
LabLaboratory
Flow
Duration20 days
RouteOral
Temperature
Concentration50-100 mg/kg/day
NotesPeripubertal male rat assay
Described effects
Effect on estrogen: Reduced seminal vesicles and prostate weights
Literature references
Ashby, J., Lefevre, P.A.(2000). The peripubertal male rat assay as an alternative to the Hershberger castrated male rat assay for the detection of anti-androgens, oestrogens and metabolic modulators.J. Appl. Toxicol., 20: 35-47
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.