ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Methoxychlor
Study details
Groupmammalian
OrganismCD-1 mouse, female
TissueUterus
AgeImmature (17 days)
InVivoIn vivo
LabLaboratory
Flow
Duration3 days
RouteSubcutaneous
Temperature22°C
Concentration10-1000 mg/kg/day
NotesMouse uterotrophic assay; dose range: 0.001-1000 mg/kg
Described effects
Effect on estrogen: Dose-dependent uterotrophic activity
Literature references
Shelby, M.D., Newbold, R.R., Tully, D.B., Chae, K., Davis, V.L.(1996). Assessing environmetal chemicals for estrogenicity using a combination of in vitro and in vivo assays.Environ. Health Perspect., 104: 1296-1300
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.