ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Methoxychlor
Study details
Groupfish
OrganismCarassius auratus (Goldfish)
TissueAR
Age
InVivoIn vitro
LabLaboratory
Flow
Duration
Route
Temperature
Concentrationup to 25 µM
NotesCompetitive binding studies using cytosolic fractions from brain and gonads
Described effects
suspected no endocrine effect
No significant binding to AR in brain and ovaries
suspected endocrine effect
RBA to testosterone at 50%: 0.008%
Literature references
Wells, K., Van Der Kraak, G.(2000). Differential binding of endogenous steroids and chemicals to androgen receptors in rainbow trout and goldfish.Environ. Toxicol. Chem., 19: 2059-2065
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.