ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Methoxychlor
Study details
Groupmammalian
OrganismHuman
TissueMCF-7 cells
Age
InVivoIn vitro
LabLaboratory
Flow
Duration
Route
Temperature
Concentration
Notes
Described effects
Effect on estrogen: RBA to [3H]-estradiol < 0.004%
Literature references
vom Saal, F.S., Nagel, S.C., Palanza, P., Boechler, M., Parmigiani, S., Welshons, W.V.(1995). Estrogenic pesticides: binding relative to estradiol in MCF-7 cells and effects of exposure during fetal life on subsequent territorial behaviour in male mice.Toxicol. Lett., 77: 343-350
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.