ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Methoxychlor
Study details
Groupmammalian
OrganismCF1 mouse, female
Tissue
AgeAdult
InVivoIn vivo
LabLaboratory
Flow
DurationDay 11 to 17 of pregnancy
RouteOral
Temperature
Concentration1-5000 µg/30 µl vehicle
NotesDaily dosing of chemicals in 30 µl corn oil
Described effects
suspected endocrine effect
Male offspring: altered territorial behaviour
Literature references
vom Saal, F.S., Nagel, S.C., Palanza, P., Boechler, M., Parmigiani, S., Welshons, W.V.(1995). Estrogenic pesticides: binding relative to estradiol in MCF-7 cells and effects of exposure during fetal life on subsequent territorial behaviour in male mice.Toxicol. Lett., 77: 343-350
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.