ED North Database | Lead |
Study details | Group | mammalian | Organism | Human | Tissue | | Age | 20-45 years | InVivo | In vivo | Lab | Field | Flow | | Duration | > 2 years | Route | Occupational | Temperature | | Concentration | | Notes | Long-term average blood Pb concentration < 400 µg/l |
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Described effects | | suspected endocrine effect Decreased sperm density, counts of total, motile and viable sperm and percentage and count of progressively motile sperm | | suspected endocrine effect Decrease in prostate secretory function | | suspected endocrine effect Abnormal sperm head morphology | | suspected endocrine effect Increased serum testosterone and estradiol |
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Literature references | Telisman, S., Cvitkovic, P., Jurasovic, J., Pizent, A., Gavella, M., Rocic, B.(2000). Semen quality and reproductive endocrine function in relation to biomarkers of lead, cadmium, zinc, and copper in men.Environ. Health Perspect., 108: 45-53 |
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