ED North Database | Lindane (gamma-Hexachlorocyclohexane) |
Study details | Group | mammalian | Organism | Mustela vison (Mink) | Tissue | | Age | | InVivo | In vivo | Lab | Laboratory | Flow | | Duration | Multi-generation study | Route | Food | Temperature | | Concentration | 1 mg/kg/day | Notes | Exposure from conception to maturity |
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Described effects | | suspected endocrine effect Decreased litter size | | suspected endocrine effect F3 males: decreased testis size | | Effect on thyroid hormone: F2 males: decreased serum T4 levels | | suspected no endocrine effect No effect on serum cortisol, testosterone and estradiol levels |
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Literature references | Beard, A.P., Rawlings, N.C.(1998). Reproductive effects in mink (Mustela vison) exposed to the pesticides lindane, carbofuran and pentachlorophenol in a multigeneration study.J. Reprod. Fertil., 113 95-104 |
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