ED North Database | Simazine |
Study details | Group | mammalian | Organism | Sprague-Dawley rat, female | Tissue | Uterus | Age | 19 days | InVivo | In vivo | Lab | Laboratory | Flow | | Duration | 3 days | Route | Injection | Temperature | | Concentration | 50-300 mg/kg/day | Notes | |
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Described effects | | suspected no endocrine effect No induction of ER-mediated responses |
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Literature references | Connor, K., Howell, J., Chen, I., Liu, H., Berhane, K., Sciarretta, C., Safe, S., Zacharewski, T.(1996). Failure of chloro-S-triazine-derived compounds to induce estrogen receptor-mediated responses in vivo and in vitro.Fundam. Appl. Toxicol., 30: 93-101 |
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