ED North Database | 2,2',4,4',5-Pentabromodiphenyl ether (BDE 99) |
Study details | Group | mammalian | Organism | Mouse | Tissue | Adrenocortical Y1 cells | Age | | InVivo | In vitro | Lab | Laboratory | Flow | | Duration | 24 hours | Route | | Temperature | | Concentration | 20 µM | Notes | |
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Described effects | | suspected no endocrine effect No significant inhibition of CYP11B1-dependent corticosterone synthesis |
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Literature references | Johansson, M., Larsson, C., Bergman, A., Lund, B.O.(1998). Structure-activity relationship for inhibition of CYP11B1-dependent glucocorticoid synthesis in Y1 cells by aryl methyl sulfones.Pharmacol. Toxicol., 83: 225-230 |
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