ED North Database | Cadmium |
Study details | Group | mammalian | Organism | Sprague-Dawley rat, male | Tissue | | Age | 30 days | InVivo | In vivo | Lab | Laboratory | Flow | | Duration | 60 days | Route | Drinking water | Temperature | 22°C | Concentration | 50 ppm | Notes | Calculated daily intake: 4 mg/kg body weight |
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Described effects | | Effect on gonadotropin: Decreased mean serum levels and pulse duration of LH | | Effect on gonadotropin: Increased LH pulse frequency |
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Literature references | Lafuente, A., Marquez, N., Piquero, S., Esquifino, A.I.(1999). Cadmium affects the episodic luteinizing hormone secretion in male rats: possible age-dependent effects.Toxicol. Lett., 104: 27-33 |
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