ED North Database | Methoxychlor |
Study details | Group | fish | Organism | Ictalurus punctatus (Channel catfish), female | Tissue | Liver | Age | 2 years | InVivo | In vitro | Lab | Laboratory | Flow | | Duration | 5 hours | Route | | Temperature | Room temperature | Concentration | IC50 = 14.23 µM | Notes | |
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Described effects | | Effect on estrogen: Inhibition of radiolabeled estradiol binding to ER; relative potency (%) to estradiol: 0.015 |
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Literature references | Nimrod, A.C., Benson, W.H.(1997). Xenobiotic Interaction with and Alteration of Channel Catfish Estrogen Receptor.Toxicol. Apl. Pharmacol., 147: 381-390 |
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