ED North Database | Methoxychlor |
Study details | Group | mammalian | Organism | Mouse | Tissue | Uterus | Age | Adult | InVivo | In vivo | Lab | Laboratory | Flow | | Duration | 18 hours | Route | Subcutaneous | Temperature | | Concentration | 3.75-60 mg/kg body weight | Notes | Concentration range: 1.8-60 mg/kg body weight; 2 injections 6 h apart |
|
|
Described effects | | Effect on estrogen: Increased estrogen responsive transcription of LF and G6PD mRNA transcription |
|
Literature references | Ghosh, D., Taylor, J.A., Green, J.A., Lubahn, D.B.(1999). Methoxychlor stimulates estrogen-responsive messenger ribonucleic acids in mouse uterus through a non-estrogen receptor (non-ER)alpha and non ERbeta mechanism.Endocrinology, 140: 3526-3533 |
|
|