ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Methoxychlor
Study details
Groupmammalian
OrganismHuman
TissueERalpha
Age
InVivoIn vitro
LabLaboratory
Flow
Duration
Route
Temperature
Concentration
NotesQSAR based on CoMFA; observed log RBA 17-beta-estradiol: 2
Described effects
Effect on estrogen: Calculated log RBA: -1.91
Literature references
Tong, W., Perkins, R., Xing, L., Welsh, W.J., Sheehan, D.M.(1997). QSAR models for binding of estrogenic compounds to estrogen receptor alpha and beta subtypes.Endocrinology, 138: 4022-4025
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.