| Physicochemical properties | | Chemical name NL | Dicofol (Kelthaan) | | Chemical name EN | Dicofol (Kelthane) | | CAS no | 115-32-2 | | UN | - | | Chemical formula | C14H9Cl5O | | Molecular weight | 370,5 | | Boiling point | 225°C | | Melting point | 79°C | | Density | 1,45 at 25°C | | Vapour pressure | - | | Solubility | 1,2 mg/l at 24°C | | LogKow | - | | Phase | Liquid | | Notes | | | Persistence | yes | | Degradation | | | Accumulation | |
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| Endocrien effect studies |
| Organism group |
Effect | | | bird | suspected endocrine effect
Egg shell thinning |
Show study | | bird | Effect on estrogen
Feminization of male embryos |
Show study | | bird | suspected endocrine effect
Altered (reproductive) behavior in 2nd generation |
Show study | | mammalian | suspected endocrine effect
Ovarian stromal cell hyperplasia |
Show study | | mammalian | suspected endocrine effect
Hepatocellular changes |
Show study | | mammalian | suspected endocrine effect
Inhibition of aromatase activity |
Show study | | mammalian | suspected no endocrine effect
No significant induction of cell proliferation |
Show study | | reptile | Effect on anti-estrogen
Inhibition of tritiated 17-beta-estradiol binding to ER |
Show study | | reptile | Effect on anti-estrogen
45% inhibition of R5020 binding to PR |
Show study | | yeast | Effect on estrogen
Induction of ER-mediated transcription |
Show study | | |
