| Organism group |
Effect | |
| bird | Effect on anti-estrogen
Dosing daily and thrice aweek: 18-21% egg shell thinning |
Show study |
| fish | Effect on gonadotropin
Decreased gonadotropin levels |
Show study |
| fish | suspected endocrine effect
Decreased GSI |
Show study |
| fish | Effect on steroid
Altered steroid synthesis |
Show study |
| fish | suspected endocrine effect
Sex dependent alteration of lipid metabolism required for ovarian recrudescence |
Show study |
| fish | Effect on sex steroid
Decreased plasma sex steroids |
Show study |
| fish | Effect on sex steroid
Decreased plasma and ovarian steroid levels |
Show study |
| fish | Effect on gonadotropin releasing hormone
Impaired GnRH secretion |
Show study |
| fish | Effect on gonadotropin
Impaired GTH secretion |
Show study |
| fish | Effect on gonadotropin releasing hormone
Inhibition of oLH-RH action |
Show study |
| fish | Effect on gonadotropin
Inhibition of mGTH action |
Show study |
| fish | suspected endocrine effect
Alteration of lipid metabolism required for ovarian recrudescence |
Show study |
| fish | Effect on estrogen
Induction of ER and VTG mRNA |
Show study |
| fish | Effect on thyroid hormone
Decreased plasma T3 and T4 levels |
Show study |
| fish | Effect on thyroid hormone
Decreased T3 and increased T4 levels |
Show study |
| fish | Effect on thyroid hormone
Decreased T3/T4 ratio |
Show study |
| fish | Effect on estrogen
Induction of VTG mRNA expression |
Show study |
| mammalian | Effect on gonadotropin
Increased serum LH concentrations |
Show study |
| mammalian | Effect on gonadotropin
Non significant increased serum FSH concentrations |
Show study |
| mammalian | suspected endocrine effect
Non significant decrease in serum testosterone levels |
Show study |
| mammalian | suspected no endocrine effect
No significant inhibition of estradiol binding to ER |
Show study |
| mammalian | suspected no endocrine effect
No effect on [3H]5-alpha-DHT binding to ABP |
Show study |
| mammalian | Effect on androgen
20-30% decrease in [3H]5-alpha-DHT binding to SHBG |
Show study |
| mammalian | Effect on androgen
50% inhibition in [3H]5-alpha-DHT binding to SHBG |
Show study |
| mammalian | Effect on androgen
IC50 = 160 µM |
Show study |
| mammalian | suspected no endocrine effect
No effects on serum estradiol and uterine progesterone concentrations |
Show study |
| mammalian | suspected no endocrine effect
No effects on ER binding |
Show study |
| mammalian | suspected no endocrine effect
No effects on pituitary and uterus weight |
Show study |
| mammalian | suspected no endocrine effect
No effects on serum estradiol concentrations |
Show study |
| mammalian | suspected no endocrine effect
No effects on pituitary weight |
Show study |
| mammalian | suspected no endocrine effect
No effets on ER distribition and PR binding |
Show study |
| mammalian | suspected endocrine effect
Reduced ovulation rate |
Show study |
| mammalian | suspected endocrine effect
Reduced testicular weight |
Show study |
| mammalian | suspected endocrine effect
Reduced testicular weight |
Show study |
| mammalian | suspected endocrine effect
Degeneration of Leydig cells |
Show study |
| mammalian | suspected endocrine effect
Decreased serum testosterone concentrations |
Show study |
| mammalian | Effect on anti-estrogen
Delayed vaginal opening and disrupted ovarian cycle |
Show study |
| mammalian | Effect on anti-estrogen
Decreased serum and pituitary LH and prolactin levels |
Show study |
| mammalian | suspected endocrine effect
Decreased pituitary and uterus weight |
Show study |
| mammalian | Effect on anti-estrogen
Increased pituitary FSH levels |
Show study |
| mammalian | suspected endocrine effect
10 mg/kg: increased serum estrogen |
Show study |
| mammalian | suspected endocrine effect
40 mg/kg: decreased serum estrogen |
Show study |
| mammalian | Effect on anti-estrogen
Lower estradiol benzoate induced increase in serum LH |
Show study |
| mammalian | suspected endocrine effect
Decreased uterus weight |
Show study |
| mammalian | Effect on anti-estrogen
Smaller estradiol benzoate induced decrease in pituitary LH, FSH and prolactin |
Show study |
| mammalian | suspected endocrine effect
Decreased testis weight |
Show study |
| mammalian | suspected endocrine effect
Cell abnormalities in testis |
Show study |
| mammalian | Effect on anti-androgen
Inhibition of spermatogenesis |
Show study |
| mammalian | Effect on anti-estrogen
Delayed vaginal opening and disrupted ovarian cycle |
Show study |
| mammalian | suspected endocrine effect
Reduced pituitary and uterus weight |
Show study |
| mammalian | suspected endocrine effect
At adulthood: reduced testicular weight |
Show study |
| mammalian | Effect on anti-androgen
At adulthood: reduced number of sperm and spermatids |
Show study |
| mammalian | Effect on anti-androgen
At adulthood and puberty: reduced serum testosterone levels |
Show study |
| mammalian | suspected endocrine effect
At adulthood: reduced testicular weight |
Show study |
| mammalian | Effect on anti-androgen
At adulthood: reduced number of sperm and spermatids |
Show study |
| mammalian | Effect on anti-androgen
At puberty: reduced serum testosterone levels |
Show study |
| mammalian | suspected endocrine effect
Reduced serum testosterone concentrations |
Show study |
| mammalian | suspected endocrine effect
Reduced sexual behaviour |
Show study |
| mammalian | suspected no endocrine effect
No effects on number of sperm and spermatids and testis weight |
Show study |
| mammalian | suspected no endocrine effect
No effects on reproductive function |
Show study |
| mammalian | suspected endocrine effect
Failure in implantation and fetotoxicity |
Show study |
| mammalian | suspected no endocrine effect
No effects on reproduction and maturation |
Show study |
| mammalian | suspected endocrine effect
Induction of MFO enzyme in liver of 3rd generation offspring |
Show study |
| mammalian | suspected endocrine effect
Decreased litter size |
Show study |
| mammalian | suspected endocrine effect
F3 males: decreased testis size |
Show study |
| mammalian | Effect on thyroid hormone
F2 males: decreased serum T4 levels |
Show study |
| mammalian | suspected no endocrine effect
No effect on serum cortisol, testosterone and estradiol levels |
Show study |
| mammalian | Effect on estrogen
Increased serum estradiol levels |
Show study |
| mammalian | Effect on thyroid hormone
Decreased serum T4 levels |
Show study |
| mammalian | Effect on insulin
Increased serum insulin levels |
Show study |
| mammalian | Effect on gonadotropin
Decreased basal serum LH levels |
Show study |
| mammalian | suspected endocrine effect
Reduced pregnancy rate |
Show study |
| mammalian | suspected endocrine effect
Increased thyroid follicle size |
Show study |
| yeast | suspected no endocrine effect
No estrogenic activity |
Show study |
| yeast | Effect on estrogen
Dose-dependent induction of ER-mediated gene transcription |
Show study |
