Physicochemical properties | Chemical name NL | Simazine | Chemical name EN | Simazine | CAS no | 122-34-9 | UN | - | Chemical formula | C7H12ClN5 | Molecular weight | 201,7 | Boiling point | - | Melting point | 225-227°C | Density | 1,302 at 20°C | Vapour pressure | 8,1E-7 Pa at 20°C | Solubility | 5 mg/l at 20°C | LogKow | 1,95 | Phase | Solid | Notes | | Persistence | no | Degradation | | Accumulation | |
|
|
Endocrien effect studies |
Organism group |
Effect | | mammalian | suspected no endocrine effect No induction of ER-mediated responses |
Show study | mammalian | suspected no endocrine effect No induction of ER-mediated responses |
Show study | mammalian | suspected endocrine effect Prolongation of estrous cycle: increase of days in estrus, decrease of days in diestrus |
Show study | mammalian | suspected endocrine effect Cornification of vaginal epithelium |
Show study | mammalian | Effect on anti-estrogen Decrease in circulating estradiol levels |
Show study | mammalian | suspected endocrine effect Decrease of days in estrus, increase of days in diestrus |
Show study | mammalian | Effect on anti-estrogen Decrease in circulating estradiol levels |
Show study | mammalian | suspected endocrine effect Increased incidence in breastcancer |
Show study | mammalian | Effect on catecholamine Dose-dependent inhibition of TH-mediated dopamine synthesis |
Show study | mammalian | Effect on catecholamine 100-200 µM: dose-dependent inhibition of DbH-mediated norepinephrine synthesis |
Show study | yeast | suspected no endocrine effect No ER-mediated growth |
Show study | | |