| Organism group |
Effect | |
| mammalian | suspected no endocrine effect
No interaction with ER |
Show study |
| mammalian | Effect on anti-estrogen
Mixture of dieldrin and alachlor reduced specific binding of estradiol to ER |
Show study |
| mammalian | suspected no endocrine effect
No significant reproductive toxicity |
Show study |
| mammalian | suspected endocrine effect
Increased thyroid weight |
Show study |
| mammalian | Effect on gonadotropin releasing hormone
Increase in circulating TSH levels from day 7 (reversible) |
Show study |
| mammalian | Effect on gonadotropin
Decrease in circulating T4 levels from day 7 |
Show study |
| mammalian | Effect on gonadotropin
Increase in circulating T3 levels (reversible) |
Show study |
| mammalian | Effect on thyroid hormone
Very low affinity for TRbeta |
Show study |
| mammalian | Effect on thyroid hormone
100 µM: 20% displacement of tritiated T3 from TR |
Show study |
| mammalian | suspected no endocrine effect
No affinity for transthyretin |
Show study |
| mammalian | suspected no endocrine effect
No affinity for thyroid-binding globulin |
Show study |
| mammalian | Effect on estrogen
Reduction of tritiated 17-beta-estradiol binding to ER |
Show study |
| mammalian | Effect on estrogen
Induction of estrogen-mediated gene expression (partial agonist) |
Show study |
| reptile | Effect on anti-estrogen
Inhibition of tritiated 17-beta-estradiol binding to ER |
Show study |
| reptile | suspected no endocrine effect
No PR binding |
Show study |
| yeast | Effect on estrogen
Induction of estrogen-mediated gene expression |
Show study |
