| Organism group |
Effect | |
| amphibian | Effect on progestogen
Inhibition of progesterone-induced oocyte maturation |
Show study |
| crustacean | suspected endocrine effect
Slightly increased male to female sex ratio (not significant) |
Show study |
| fish | Effect on estrogen
Inhibition of radiolabeled estradiol binding to ER |
Show study |
| fish | Effect on estrogen
Relative potency to 17-beta-estradiol: 0.00002 |
Show study |
| fish | Effect on estrogen
Slightly increased serum vitellogenin |
Show study |
| fish | suspected no endocrine effect
No significant binding to AR in brain and ovaries |
Show study |
| fish | suspected endocrine effect
RBA to testosterone at 50%: 0.008% |
Show study |
| fish | suspected no endocrine effect
No binding to AR in brain, testes and ovaries |
Show study |
| fish | suspected no endocrine effect
No significant induction of vitellogenesis |
Show study |
| fish | suspected no endocrine effect
No effect on sex ratio |
Show study |
| fish | suspected no endocrine effect
No depreciation in reproductive capability |
Show study |
| fish | Effect on estrogen
Inhibition of radiolabeled estradiol binding to ER; relative potency (%) to estradiol: 0.015 |
Show study |
| mammalian | Effect on estrogen
RBA to [3H]-estradiol < 0.004% |
Show study |
| mammalian | suspected endocrine effect
Male offspring: altered territorial behaviour |
Show study |
| mammalian | Effect on estrogen
10% reduction of tritiated 17-beta-estradiol binding to ER |
Show study |
| mammalian | suspected no endocrine effect
No effect on tritiated 5-alpha-DHT binding on AR |
Show study |
| mammalian | Effect on androgen
40-50% decrease in tritiated 5-alpha-DHT binding to ABP |
Show study |
| mammalian | suspected no endocrine effect
No effect on tritiated 5-alpha-DHT binding to SHBG |
Show study |
| mammalian | Effect on estrogen
0.5-500 mg/kg: increased relative uterus weight |
Show study |
| mammalian | Effect on estrogen
100-500 mg/kg: increased peroxidase activity |
Show study |
| mammalian | Effect on estrogen
500 mg/kg: induction of cell proliferation |
Show study |
| mammalian | Effect on estrogen
Inhibition of tritiated 17-beta-estradiol binding to ER |
Show study |
| mammalian | Effect on estrogen
Relative binding affinity: 0.0000031 |
Show study |
| mammalian | suspected no endocrine effect
No interaction with ER |
Show study |
| mammalian | suspected no endocrine effect
No induction of ER-mediated activity |
Show study |
| mammalian | Effect on estrogen
Dose-dependent uterotrophic activity |
Show study |
| mammalian | Effect on estrogen
Increased estrogen responsive transcription of LF and G6PD mRNA transcription |
Show study |
| mammalian | Effect on estrogen
RTA for ERalpha compared to radiolabeled 17-beta-estradiol (%): 9 |
Show study |
| mammalian | Effect on estrogen
RTA for ERbeta compared to radiolabeled 17-beta-estradiol (%): 2 |
Show study |
| mammalian | Effect on estrogen
Induction of cell proliferation |
Show study |
| mammalian | Effect on estrogen
Stimulation of transcriptional activity of ER |
Show study |
| mammalian | Effect on estrogen
Calculated log RBA: -1.91 |
Show study |
| mammalian | Effect on estrogen
Calculated log RBA: -0.68 |
Show study |
| mammalian | Effect on estrogen
Predicted log RBA: -2.19 |
Show study |
| mammalian | Effect on estrogen
Predicted log RBA: -1.08 |
Show study |
| mammalian | Effect on estrogen
Alteration of estrogen-mediated gene expression |
Show study |
| mammalian | Effect on estrogen
Inhibition of fluorescent ligand ES1 binding to ER |
Show study |
| mammalian | Effect on estrogen
RBA compared to estradiol: 0.007-0.02% |
Show study |
| mammalian | Effect on estrogen
Inhibition of tritiated 17-beta-estradiol binding to ER |
Show study |
| mammalian | Effect on estrogen
Potency relative to 17-beta-estradiol: 0.00001 |
Show study |
| mammalian | Effect on estrogen
Induction of cell proliferation |
Show study |
| mammalian | Effect on estrogen
Induction of estrogen-dependent transcription |
Show study |
| mammalian | Effect on anti-androgen
Inhibition of DHT-induced activity (antagonist) |
Show study |
| mammalian | suspected no endocrine effect
No effect on reproductice organs weights |
Show study |
| mammalian | Effect on estrogen
Reduced seminal vesicles and prostate weights |
Show study |
| reptile | suspected no endocrine effect
No interaction with ER |
Show study |
| yeast | Effect on estrogen
Induction of ER-mediated gene expression |
Show study |
| yeast | Effect on estrogen
Induction of ER-mediated gene expression |
Show study |
| yeast | suspected no endocrine effect
No estrogenic activity |
Show study |
