Bisphenol-A: verschil tussen versies

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(See also)
(See also)
Regel 39: Regel 39:
== See also ==
== See also ==
[ Bisphenol-A on ED North Database]
[ Bisphenol-A on the ED North Database]
[ Bisphenol-A on the Ecotox Database]
[ Bisphenol-A on the Ecotox Database]

Versie van 25 sep 2009 om 11:00

Definition of Bisphenol-A:
Bisphenol-A is also known as 4,4’-Isopropylidenediphenol. At room temperature it occurs as a white powder or in flakes. [1]
This is the common definition for Bisphenol-A, other definitions can be discussed in the article



The total amount of bisphenol-A manufactured in 2005 within the EU was estimated at approximately 1.150.000 tonnes. This large amount was mainly produced to manufacture polycarbonate, witch is a widely used plastic.[2]

In water bisphenol A is moderately soluble, 300 mg/l, and considered to have a moderate tendency to adsorb to suspended particles and sediments. It has a very low tendency to evaporate into the atmosphere where most of it will be degraded in less than a day. In water and soils it is rather stable, although it can readily be biodegraded. The environmental half-life is only 3 to 8 days and a 100% removal of environmental contamination can occur within 17 days. In anoxic sediments bisphenol A can be created from the degradation of TBBP-A.[1]

Bisphenol A has a low tendency to bioaccumulate. Therefore in poses a low toxicity threat by biomagnification towards marine mammals. Bisphenol A become lethal when mammals consume each day more than 33 mg of it per kg of body weight.[1]

Bisphenol A exhibits endocrine disrupting effects. In gastropods concentrations bellow 100 µg/l have been shown cause reduced penis sizes in males and enhanced oocyte production in females. The latter results in an increased embryo production at low bisphenol A concentrations. The latter effect has even been demonstrated in some gastropod species at concentrations of only 100 ng/l. [2] It demonstrates a moderate acute toxicity towards aquatic species. Most species start dying at concentrations above 1 mg/l. [3]

Environmental standards and legislation

Included in the water framework list of priority substances

See also

Bisphenol-A on the ED North Database

Bisphenol-A on the Ecotox Database


  1. 1,0 1,1 1,2 February 2008 Updated European Risk Assessment Report 4,4’-ISOPROPYLIDENEDIPHENOL (BISPHENOL-A)
  2. 2,0 2,1 ECHA 2008 ANNEX XV RESTRICTION REPORT Bisphenol-A
  3. August 24 2009