Genomics

Uit Kust Wiki
Versie door Francisco.souzadias (Overleg | bijdragen) op 20 jul 2012 om 09:21

(wijz) ← Oudere versie | Huidige versie (wijz) | Nieuwere versie → (wijz)
Ga naar: navigatie, zoeken
Definition of Genomics:
the branch of molecular genetics concerned with the study of genomes, specifically the identification and sequencing of their constituent genes and the application of this knowledge in medicine, pharmacy, agriculture, etc[1]


Genomics includes:

  • Functional genomics -- the characterization of genes and their mRNA and protein products.
  • Structural genomics -- the dissection of the architectural features of genes and chromosomes.
  • Comparative genomics -- the evolutionary relationships between the genes and proteins of different species.
  • Epigenomics (epigenetics) -- DNA methylation patterns, imprinting and DNA packaging.
  • Pharmacogenomics -- new biological targets and new ways to design drugs and vaccines. [2]


The birth of the term "genomics" was documented as follows: "For the newly developing discipline of mapping/sequencing (including analysis of the information) we have adopted the term GENOMICS. We are indebted to T. H. Roderick of the Jackson Laboratory, Bar Harbor, Maine, for suggesting the term. The new discipline is born from a marriage of molecular and cell biology with classical genetics and is fostered by computational science." [3]
This is the common definition for Genomics, other definitions can be discussed in the article

References

  1. Collins English Dictionary – Complete and Unabridged © HarperCollins Publishers 1991, 1994, 1998, 2000, 2003
  2. Based on WordNet 3.0, Farlex clipart collection. © 2003-2012 Princeton University, Farlex Inc.
  3. Victor A. McKusick and Frank H. Ruddle. A new discipline, a new name, a new journal [editorial]. Genomics 1987 Sep;1:1-2.)