ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
DDT
Study details
Groupmammalian
OrganismHuman
TissueHepG2 cells
Age
InVivoIn vitro
LabLaboratory
Flow
Duration
Route
Temperature
ConcentrationLOEC = 1 µM
NotesHepG2 cells transfcted with 2 overlapping EREs
Described effects
Effect on estrogen: Induction of estrogen-mediated transcription
Literature references
Massaad, C., Barouki, R.(1999). An assay for the detection of xenoestrogens based on a promoter containing overlapping EREs.Environ. Health Perspect., 107: 563-566
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.