ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
DDT
Study details
Groupamphibian
OrganismAmbystomia tigrinum (Tiger Salamander)
TissueGonad
AgeLarva
InVivoIn vivo
LabLaboratory
FlowSemi-static
Duration28 days
RouteWater
Temperature
Concentration0.01 ppm
Notes
Described effects
Effect on anti-estrogen: Females: decreased müllerian duct epithelial area
Effect on anti-estrogen: Females: inhibition of 17-beta-estradiol action
suspected no endocrine effect
Males: no significant effect on müllerian duct
suspected no endocrine effect
Both sexes: no effect on wolffian ducts
suspected no endocrine effect
Males: no significant effect on müllerian duct
suspected no endocrine effect
Both sexes: no effect on wolffian ducts
Literature references
Clark, E.J., Norris, D.O., Jones, R.E.(1998). Interactions of gonadal steroids and pesticides (DDT, DDE) on gonaduct growth in larval tiger salamanders, Ambystomia tigrinum.Gen. Comp. Endocrinol., 109: 94-105
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.