ED North Database | Lindane (gamma-Hexachlorocyclohexane) |
Study details | Group | mammalian | Organism | Wistar rat, male offspring | Tissue | | Age | 7 months | InVivo | In vivo | Lab | Laboratory | Flow | | Duration | | Route | Maternal transfer | Temperature | | Concentration | 30 mg/kg | Notes | Single dose to mother on day 15 of pregnancy |
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Described effects | | suspected endocrine effect Reduced serum testosterone concentrations | | suspected endocrine effect Reduced sexual behaviour | | suspected no endocrine effect No effects on number of sperm and spermatids and testis weight |
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Literature references | Dalsenter, P.R., Faqi, A.S., Chahoud, I.(1997). Serum Testosterone and Sexual behaviour in Rats after Prenatal Exposure to Lindane.Bull. Environ. Contam. Toxicol., 59: 360-366 |
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