ED North Database | Hexachlorobenzene |
Study details | Group | mammalian | Organism | Sprague-Dawley rat | Tissue | | Age | | InVivo | In vivo | Lab | Laboratory | Flow | | Duration | 2-generation study | Route | Food | Temperature | | Concentration | 40 ppm | Notes | Concentration range: 0.32-40 ppm |
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Described effects | | suspected no endocrine effect No effect on fertility | | suspected endocrine effect F1: increased incidence of parathyroid adenomas |
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Literature references | Arnold, D.L., Moodie, C.A., Charbonneau, S.M., Grice, H.C., McGruire, P.F., Bryce, F.R., Collins, B.T., Zawidzka, Z.Z. et al.(1985). Long-term toxicity of hexachlorobenzene in the rat and the effect of dietary vitamin A.Food Chem.Toxicicol., 23: 779-793 |
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