ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
PCB
Study details
Groupfish
OrganismPlatichthys flesus (Flounder)
Tissue
Age
InVivoIn vivo
LabField
Flow
Duration
RouteEnvironmental contamination
Temperature
Concentration
NotesFish collected in United Kingdom estuaries, the North Sea and the Irish Sea; total PAK in liver: 48-365 µg/kg wet weight (predominantly naphtalene and its alkyl derivatives); organochlorines in liver: PCBs (predominantly), dieldrin, alpha and gamma hexachlorocyclohexane, DDT and metabolites
Described effects
Effect on estrogen: Increased plasma VTG levels compared to control site
Effect on estrogen: Occurrence of ovotestis and intersex
suspected endocrine effect
Increased hepatic EROD activity
Literature references
Matthiessen, P., Allen, Y.T., Allchin, C.R., Feist, S.W., Kirby, M.F., Law, R.J., Scott, A.P., Thain, J.E., Thomas, K.V.(1998). Oestrogenic endocrine disruption in flounder (Platichthys flesus L.) from United Kingdom estuarine and marine waters.Sci. Ser., Tech. Rep., CEFAS, Lowestoft, (107), 48pp
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
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