ED North Database | Anthracene |
Study details | Group | mammalian | Organism | Mouse | Tissue | Hepa lclc7 cells | Age | | InVivo | In vitro | Lab | Laboratory | Flow | | Duration | 24 hours | Route | | Temperature | | Concentration | EC50: 42 to 150 nM | Notes | Contributes to TCDD-like activity of air particulate matter |
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Described effects | | Effect on anti-estrogen: Induction of AhR-mediated gene expression | | Effect on anti-estrogen: Relative potency to TCDD: 0.0001 |
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Literature references | Clemons, J.H., Allan, L.M., Marvin, C.H., Wu, Z., McCarry, B.E., Bryant, D.W., Zacharewski, T.(1998). Evidence of estrogen- and TCDD-like activities in crude and fractionated extracts of PM10 air particulate material using in vitro gene expression assay.Environ. Sci. Technol., 32: 1853-1860 |
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