ED North Database | Anthracene |
Study details | Group | mammalian | Organism | Chinese hamster | Tissue | CHO cells cotransfected with a hAR | Age | | InVivo | In vitro | Lab | Laboratory | Flow | | Duration | 24 hours | Route | | Temperature | 37°C | Concentration | 10 µM | Notes | AR assay; dose range: 0.05-10 µM |
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Described effects | | Effect on anti-androgen: Slight inhibition of hAR transactivation by R1881 |
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Literature references | Vinggaard, A.M., Hnida, C., Larsen, J.C.(2000). Environmental polycyclic aromatic hydrocarbons affect androgen receptor activation in vitro.Toxicology, 145: 173-183 |
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