ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Methoxychlor
Study details
Groupmammalian
OrganismRabbit, female
TissueUterus
AgeJuvenile
InVivoIn vitro
LabLaboratory
Flow
Duration
Route
Temperature
Concentration100 µM
Notes
Described effects
Effect on estrogen: 10% reduction of tritiated 17-beta-estradiol binding to ER
Literature references
Danzo, B.J.(1997). Environmental xenobiotics may disrupt normal endocrine function by interfering with the binding of physiological ligands to steroid receptors and binding proteins.Environ. Health Perspect., 105(3): 294-301
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.