ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Methoxychlor
Study details
Groupmammalian
OrganismRat
TissueMtT/E-2 cells
Age
InVivoIn vitro
LabLaboratory
Flow
Duration24 hours
Route
Temperature
Concentration10-100 µM
NotesRat pituitary tumor cell line; concentration range: 0.1-100 µM
Described effects
Effect on estrogen: Induction of estrogen-dependent transcription
Literature references
Maruyama, S., Fujimoto, N., Yin, H., Ito, A.(1999). Growth stimulation of a rat pituitary cell line MtT/E-2 by environmental estrogens in vitro and in vivo.Endocr. J., 46: 513-520
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.