ED North Database | Methoxychlor |
Study details | Group | fish | Organism | Carassius auratus (Goldfish) | Tissue | AR | Age | | InVivo | In vitro | Lab | Laboratory | Flow | | Duration | | Route | | Temperature | | Concentration | up to 25 µM | Notes | Competitive binding studies using cytosolic fractions from brain and gonads |
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Described effects | | suspected no endocrine effect No significant binding to AR in brain and ovaries | | suspected endocrine effect RBA to testosterone at 50%: 0.008% |
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Literature references | Wells, K., Van Der Kraak, G.(2000). Differential binding of endogenous steroids and chemicals to androgen receptors in rainbow trout and goldfish.Environ. Toxicol. Chem., 19: 2059-2065 |
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