ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Octylphenol
Study details
Groupmammalian
OrganismHuman
TissueERalpha
Age
InVivoIn vitro
LabLaboratory
Flow
Duration18 hours
Route
TemperatureAmbient
Concentration
NotesHuman ERalpha expressed in Sf9 insect cell line; RBA-assay for hER
Described effects
Effect on estrogen: RBA compared to radiolabeled 17-beta-estradiol (%): 0.02
Literature references
Kuiper, G.G.J.M., Lemmen, J.G., Carlsson, B., Corton, J.C., Safe, S.H., van der Saag, P.T., van der Burg, B., Gustafsson, J.A.(1998). Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor beta.Endocrinology, 139: 4252-4263
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.