ENDIS-RISKS
Endocrine Disruption in the Scheldt estuary:
distribution, exposure and effects
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ED North Database
Octylphenol
Study details
Groupfish
OrganismRainbow trout
Tissue
AgeJuvenile (18 months)
InVivoIn vivo
LabLaboratory
FlowFlow through
Duration1 week
RouteIntraperitoneal
Temperature10C
Concentration5-50 mg/kg body weight
Notes
Described effects
Effect on estrogen: Upregulation of hepatic ER
Effect on estrogen: Induction of zonaradiata proteins
Effect on estrogen: Additivity in combination with butylbenzylphtalate or 17-beta-estradiol
Literature references
Knudsen, F.R., Arukwe, A., Pottinger, T.G.(1998). The in vivo effect of combinations of octylphenol, butylbenzylphtalate and estradiol on liver estradiol receptor modulation and induction of zona radiata proteins in rainbow trout: no evidence of synergy.Environ. Pollut., 103: 75-80
Data compiled by the Research Group Environmental Toxicology, Laboratory of Environmental Toxicology and Aquatic Ecology, Ghent University, Belgium.
For queries about the data, please contact Colin Janssen or Tim Verslycke .
More info about the contents and the structure of the database can be found on the about screen.