ED North Database | Tetrabromobisphenol A |
Study details | Group | mammalian | Organism | Human | Tissue | | Age | | InVivo | In vitro | Lab | Laboratory | Flow | | Duration | Overnight | Route | | Temperature | 4°C | Concentration | IC50 = 7.7 nM | Notes | T4-transthyretin competition binding study |
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Described effects | | Effect on thyroid hormone: Displacement of T4 from transthyretin |
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Literature references | Meerts, I.L.T.M., van Zanden, J.J., Luijks, E.A.C., van Leeuwen-Bol, I., Marsh, G., Jakobsson, E., Bergman, A., Brouwer, A.(2000). Potent competitive interactions of some brominated flame retartands and related compounds with human transthyretin in vitro.Toxicol. Sci., 56: 95-104 |
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