This REPHY dataset includes long-term time series on marine phytoplankton and physico-chemical measures, since 1987, along the whole French metropolitan coast. Some of these data are shared with those of the following regional networks: SRN (Hauts-de-France), RHLN (Normandy), ARCHYD (Arcachon), RSLHYD (Mediterranean lagoons). REPHY dataset from overseas departments (Martinique, Guadeloupe and French Guiana in West Atlantic waters; Reunion Island and Mayotte in Indian Ocean) will be available later. Phytoplankton data essentially cover microscopic taxonomic identifications and counts, but also pigments measures and flux cytometry measures in few regions. Physico-chemical measures include temperature, salinity, turbidity, dissolved oxygen, nutrients and chlorophylle a.