IMIS | Flanders Marine Institute
 

Flanders Marine Institute

Platform for marine research

IMIS

Publications | Institutes | Persons | Datasets | Projects | Maps
[ report an error in this record ]basket (0): add | show Printer-friendly version

Eicosanoids from the tropical red alga Murrayella periclados
Bernart, M.W.; Gerwick, W.H. (1994). Eicosanoids from the tropical red alga Murrayella periclados. Phytochemistry 36(5): 1233-1240
In: Phytochemistry. PERGAMON-ELSEVIER SCIENCE LTD: Oxford. ISSN 0031-9422, more
Peer reviewed article  

Available in Authors 

Keywords
    Aquatic drugs; Chemical composition; Fatty acids; Metabolites; Pharmacology; Seaweeds; Murrayella periclados (C.Agardh) F.Schmitz, 1893 [WoRMS]; Rhodomelaceae J.E. Areschoug, 1847 [WoRMS]; Marine

Authors  Top 
  • Bernart, M.W.
  • Gerwick, W.H.

Abstract
    Lipid extracts of several collections of the tropical red marine alga Murrayella periclados were found to be rich sources of eicosanoids more commonly associated with mammalian systems, including 12S-hydroxyeicosapentaenoic acid, 12S-hydroxyeicosatetraenoic acid, (6E)-leukotriene B4, and erythro and threo diastereomers of hepoxilins B3 and B4. This is the first report of leukotriene or hepoxilin B sub(4) natural products from a plant, and several spectroscopic features of these molecules are reported herein for the first time. Two conjugated triene-containing acids recently reported from another red alga, 5Z,7E,9E,14Z,17Z-eicosapentaenoic acid and 5E,7E,9E,14Z,17Z-eicosapentaenoic acid, were also found in the algal extract. A 12-lipoxygenase initiated biosynthetic origin is proposed for most of these Murrayella oxylipins.

All data in IMIS is subject to the VLIZ privacy policy Top | Authors