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Amphibian haemotology: metamorphosis-related changes in blood cells
Rosenkilde, P.; Sorensen, I.; Phaff Ussing, A. (1995). Amphibian haemotology: metamorphosis-related changes in blood cells. Neth. J. Zool. 45(1-2): 213-215
In: Netherlands Journal of Zoology. E.J. Brill: Leiden. ISSN 0028-2960, more
Peer reviewed article  

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  • Rosenkilde, P.
  • Sorensen, I.
  • Phaff Ussing, A.

    amphibian metamorphosis is a rapid process to meet the demands of a new life-form. As a part of metamorphosis, blood cell populations are renewed. In erthrocytes, this involves a shift to a new 'terrestrial' type of hemoglobinwith lower oxigen affinity. The leukocytes must maintain protection against infection and at the same time allow for the appearance of new tisseu components. Antibody-producing cells of larval origin are substituted by postmetamorphic cells providing a specific, polyclonal antibody repertoire. As postmetamorphic tissue antigens appear, immune functions that might otherwise lead to autoimmune reactivity, are suppressed.

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