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α-Nemertides, a novel family of marine peptide neurotoxins from ribbon worms
Tytgat, J. (2017). α-Nemertides, a novel family of marine peptide neurotoxins from ribbon worms. KULeuven: Leuven.

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Document type: Summary

Keyword
    Marine

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  • VLIZ Science Symposium: The Ocean and Human Health, more

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Abstract
    Ribbon worms (nemerteans) are marine predators, which capture their prey using a proboscis containing a mixture of toxins which brings on rapid paralysis. We have discovered a novel family of peptides (a-nemertides), of which one causes death in green crabs and targets invertebrate voltage-gated sodium channels at low nanomolar concentrations, suggesting a role as drug lead for novel insecticidal and anti-parasitic agents.

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