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Defence mechanisms against heavy metal exposure in fish with different sensitivities to stress: interactions and dynamics of proteins and hormones

Period: January 2007 till December 2010
Status: Completed

Institutes (2)  Top 
  • Universiteit Antwerpen; Faculteit Wetenschappen; Departement Biologie; Onderzoeksgroep Systemisch Fysiologisch en Ecotoxicologisch Onderzoek (SPHERE), more, promotor
  • Vlaamse overheid; Beleidsdomein Economie, Wetenschap en Innovatie; Fonds voor Wetenschappelijk Onderzoek - Vlaanderen (FWO), more, sponsor

The aim of this research is to assess whether gill cells of fish with a different sensitivity to copper exposure show intracellular differences in protein expression patterns of transporters, carriers and metal binding protein as well as in proteins and enzymes involved in the defence mechanisms against oxidative stress. We want to evaluate the dynamics of these patterns in three fish species under sublethal copper exposure and in addition determine the role of the changes in hormonal status on these processes.

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