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Further investigation of the Mediterranean sponge Axinella polypoides: isolation of a new cyclonucleoside and a new betaine
Menna, M.; Aiello, A.; D'Aniello, F.; Fattorusso, E.; Imperatore, C.; Luciano, P.; Vitalone, R. (2012). Further investigation of the Mediterranean sponge Axinella polypoides: isolation of a new cyclonucleoside and a new betaine. Mar. Drugs 10(11): 2509-2518. https://dx.doi.org/10.3390/md10112509
In: Marine Drugs. Molecular Diversity Preservation International (MDPI): Basel. ISSN 1660-3397; e-ISSN 1660-3397, more
Peer reviewed article  

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Keywords
    Axinella polypoides Schmidt, 1862 [WoRMS]; Axinellidae Carter, 1875 [WoRMS]
    Marine/Coastal
Author keywords
    natural products; sponges; Axinellidae; pyrrole-imidazole alkaloids; taxon-specificity

Authors  Top | Dataset 
  • Menna, M.
  • Aiello, A.
  • D'Aniello, F.
  • Fattorusso, E.
  • Imperatore, C.
  • Luciano, P.
  • Vitalone, R.

Abstract
    An exhaustive exploration into the metabolic content of the Mediterranean sponge Axinella-polypoides resulted in the isolation of the new betaine 5 and the new cyclonucleoside 8. The structures of the new metabolites were elucidated by spectroscopic methods assisted by computational methods. The analysis also provided evidence that the sponge does not elaborate pyrrole-imidazole alkaloids (PIAs) but, interestingly, it was shown to contain two already known cyclodipeptides, compounds 9 (verpacamide A) and 10.

Dataset
  • CorMedNet- Distribution and demographic data of habitat-forming invertebrate species from Mediterranean coralligenous assemblages between 1882 and 2019., more

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